The one of the keys to healthy estrogen metabolism is to ensure that the estrogen metabolites head down the right path. Enter DIM.
Diindolylmethane, or DIM, is a plant-compound found in Brassica veggies such as broccoli, bok choy, cauliflower, cabbage, and Brussels sprouts. Researchers have found that this interesting little compound is quite beneficial in promoting estrogen metabolism.
Studies show that when DIM is ingested, it not only encourages its own metabolism, but that of estrogen. While it is not an estrogen or even an estrogen-mimic, its metabolic pathway exactly coincides with the metabolic pathway of estrogen. When these pathways intersect, DIM favorably adjusts the estrogen metabolic pathways by simultaneously increasing the good estrogen metabolites and decreasing the bad 16-alpha-hydroxyestrone.
The research confirms this action. In a study from Epidemiology, American researchers took urine samples from 34 healthy postmenopausal women. They then added 10 grams of broccoli a day to the women's diets. After taking another urine sample, researchers found that this dietary change significantly increased the 2-hydroxyestrone to 16-alpha-hydroxyestrone ratio.